In addition, subgroup analysis revealed elevated YAP levels in the tumor tissues of patients with T stage 3-4, lymph node metastasis, and TNM stage III-IV compared with patients with T stage 1-2, no lymph node metastasis, and TNM stage I-II (Figure 1C-E). The gene discussed is YAP1; the disease is metastatic malignant neoplasm in the lymph nodes.