AKT1 and neoplasm: Further functional analysis showed that miRNA regulatory network genes may participate in the occurrence and development of PM through multiple tumor-associated pathways, including PI3K/Akt signaling pathway, p53 signaling pathway, and Wnt signaling pathway, etc. We found that KIF23 and VPS37B expressions were closely correlated with several immune cell infiltrations, infiltration levels of these cells had a significant impact on survival outcome.