The recipient mice that received Prmt1 KO leukemia cells overexpressed Rpl29 exhibited shorter survival (median survival: Prmt1 KO + Rpl29 vs Prmt1 KO+Vector was 23 days vs not reached after monitoring for 50 days), more prominent splenomegaly and spleen weight than those that received Prmt1 KO leukemia cells overexpressed empty vector (Figure 6C–E). This evidence concerns the gene PRMT1 and Splenomegaly.