PRMT1 and leukemia: The recipient mice that received leukemia cells reconstituted with PRMT1WT but not PRMT1E153Q died earlier than those that received leukemia cells reconstituted with empty vector (median survival: Prmt1 KO+PRMT1WT vs Prmt1 KO+PRMT1E153Q was 21 days vs not reached after monitoring for 65 days; Figure 3C).