PRMT1 and chronic myelogenous leukemia, BCR-ABL1 positive: To investigate whether PRMT1 regulates LSCs in a methyltransferase activity‐dependent manner, BM and spleen cells from primary WT CML mice transduced with pCDH‐vector, pCDH‐wild‐type PRMT1 (PRMT1WT) or enzymatic mutant PRMT1 (PRMT1E153Q) lentivirus were transplanted into secondary recipients to induce CML (Figure S6A, Supporting Information).