Through flow cytometric analysis of tumor‐free lymph nodes draining the primary tumor site in melanoma patients, we and others identified both CD1a+ dermal DC (DDC) and LC subsets, migrated from the skin, and CD1a− LNR‐cDC subsets, derived from blood‐borne precursors [67, 101, 102]. This evidence concerns the gene CD1A and neoplasm.