A panoply of RTKs and nRTKs, including but not limited to platelet-derived growth factor receptor (PDGFR), epidermal growth factor receptor (EGFR), fibroblast growth factor receptor (FGFR), vascular endothelial growth factor receptor (VEGFR) family, anexelekto (AXL), insulin-like growth factor receptor (IGFR), mesenchymal-epithelial transition factor (MET), etc., play pivotal roles in fostering hyperproliferation, angiogenesis, evasion of apoptosis, cellular invasion, tumor cell motility, tumor advancement, metastasis, and resistance to therapeutic agents [24]. The gene discussed is KDR; the disease is neoplasm.