In contrast to the Th-MYCN model (Fig. 1b,c), anti-GD2 therapy alone did not mediate a substantial anti-tumor effect though the addition of TETA produced a remarkable anti-tumor effect (median survival: 29 days vs. 19 days in Saline + anti-GD2, p = 0.0091) leading to durable eradication in ~40% of animals (Fig. 7f). This evidence concerns the gene MYCN and neoplasm.