ERBB2 and neoplasm: For theranostic purposes in patients with HER2-positiveBC, [111In]In-DOTA-trastuzumab IgG, F(ab')22 or Fab would be administered for SPECT/CT imaging priortoRIT, but our intent was to capture any potential cytotoxic effectsof α-particle emissions of 225Ac that may decreasethe tumor or organ weight and thus change the %ID/g values, sincethe biodistribution of the 111In-labeled RICs was usedto estimate dosimetry of 225Ac-labeled RICs.