The results of the MBP analysis revealed a significant increase in CSF Myelin Basic Protein levels in all atypical Parkinsonian conditions compared to PD in cohort 1 (MSA vs. PD p = 0.019; DLB vs. PD p = 0.008; PSP/CBD vs. PD p = 0.012) (Fig. 1). This evidence concerns the gene MBP and Parkinson disease.