Suggesting specificity for MS, EBNA1-targeting antibody responses are reported to be unchanged in patients with myelin oligodendrocyte glycoprotein-antibody associated disease (MOGAD) [11] and a broader anti-EBV T cell receptor repertoire has recently been described to be specifically associated with MS but absent in aquaporin 4-antibody positive neuromyelitis optica spectrum disorder (NMOSD), MOGAD, or in Susac’s syndrome [12]. The gene discussed is AQP4; the disease is myeloid sarcoma.