STING1 and infection: Noncanonical signaling downstream of STING includes STING/PERK, NF‐κB, and IFN regulatory factor 3 (IRF3).[460] STING functions in cellular senescence, autophagy, proliferation, and death.[461, 462, 463] cGAS/STING signaling is a key crossroad between the immune system and multiple diseases, such as infection, fibrosis, and malignancy.