These activated cells produce proinflammatory cytokines and chemokines, including IL‐6, IP‐10, monocyte chemotactic protein 1 (MCP1), interferon γ (IFNγ), and macrophage inflammatory protein 1α (MIP1α).[260, 261, 262] These proinflammatory factors recruit monocytes, T cells, and macrophages to the infection site, causing a positive feedback loop in the overproduction of cytokines that results in a cytokine storm. This evidence concerns the gene CCL2 and infection.