TGFB1 and renal fibrosis: revealed that transgenic expression of Twist1 (encoding twist family bHLH transcription factor 1) or Snail1 is critical for prolonged TGF‐β‐induced G2 arrest of tubular cells that still reside associated with the basement membrane.[122] Furthermore, in the above renal fibrosis mouse model, conditional Twist or Snail knockout in proximal tubular cells inhibited EMT and alleviated renal fibrosis.