IL10 and parasitic infectious disease: In parasitic infection models, T helper 1 (Th1) cell responses trigger the regression of fibrosis, whereas the induction of Th2 responses promotes fibrosis.[202] Natural Tregs also contribute to the alleviation of fibrosis during parasitic infection via the production of IL‐10.[74] The current understanding of the principal components and interactions between HSCs and immunocytes contributes to the investigation of therapeutic targets for the regression of hepatic fibrosis.