The RNA‐binding protein YTHDC1, which is expressed mainly in AEC2s, alleviates AEC senescence by promoting the interaction between TopBP1 and MRE11, thereby facilitating DNA repair.[253] Leucine‐rich repeat kinase 2 (LRRK2) in AEC2s sharply decreases in the lungs of bleomycin‐treated mice, and its deficiency leads to accelerated cellular senescence.[254] Hence, LRRK2 plays a critical role in preventing pulmonary fibrosis. Here, LRRK2 is linked to pulmonary fibrosis.