FAP and Myocardial fibrosis: Since fibroblast activation protein (FAP) is overexpressed on cardiac myofibroblasts, engineered chimeric antigen receptor T cell (CAR‐T) cells against FAP may significantly reduce myocardial fibrosis and improve cardiac function in a cardiac fibrosis mouse model.[618] Transient anti‐fibrotic CAR‐T cells were later generated and its efficacy in reducing fibrosis and restore cardiac function was studied in animal study.[619] Nevertheless, the toxic effects of CAR‐T cells on the cardiovascular system need to be further elucidated.