The expression of ILK is increased in peritoneal fibrosis, and the ILK in the effluent of peritoneal dialysis initiates peritoneal fibrogenesis.[378] ILK also mediates the activation of EMT in renal fibrosis and HSCs and involved in IPF in a tissue‐specific manner with a specific subset of fibroblasts expressing ILK.[379] In a renal fibrosis mouse model, ILK is strongly induced and is associated with the EMT of TECs.[380] In addition, angiotensin II induces the expression of TGF‐β/SMAD signaling, which promotes ILK expression.[333]. The gene discussed is TGFB1; the disease is renal fibrosis.