The results of functional experiments revealed that the proliferation, migration, and invasion functions of colon cancer cells were enhanced after the overexpression of Lyn/RUVBL1, and the proliferation, migration, and invasion functions of colon cancer cells were weakened after the overexpression of Lyn/RUVBL1 knocked down TRIB3 (Figure 4M–O). Here, LYN is linked to malignant colon neoplasm.