The results of functional experiments revealed that the proliferation, migration, and invasion functions of colon cancer cells were enhanced after the overexpression of Lyn/RUVBL1, and the proliferation, migration, and invasion functions of colon cancer cells were weakened after the overexpression of Lyn/RUVBL1 knocked down TRIB3 (Figure 4M–O). The gene discussed is LYN; the disease is colonic neoplasm.