CD4 and psoriasis: Self‐antigens can bind to Toll‐like receptors on the surface of DCs in the dermis of patients with psoriasis, triggering DCs activation and subsequent clonal expansion of antigen‐specific CD4+ T cells.[3] To investigate the impact of decreasing self‐antigens on BMDCs maturation, we incubated BMDCs with RNA+low/mid/high polyamine+peptide before the assessment of the maturation markers (Figure 2A).