Additionally, chemokine receptors such as C-C chemokine receptor 3 (CCR3), C-C chemokine receptor 4 (CCR4), C-C chemokine receptor 8 (CCR8) and C-X-C chemokine receptor 4 (CXCR4) are also key in Th2-driven asthma. The gene discussed is CCR8; the disease is asthma.