The article by Lahham E.E., Hassasneh J.J., Adavi D.O., Ismail M.K. ‘Variants in the SARS2 gene cause HUPRA syndrome with atypical features: two case reports and review of the literature.’ [Oxf Med reports. This evidence concerns the gene SARS2 and hyperuricemia-pulmonary hypertension-renal failure-alkalosis syndrome.