However, excessive dietary arabinoxylan (10%) exerted adverse effects on the intestinal chemical barrier by reducing intestinal digestive enzyme activities and MUC2 gene expression, as well as simultaneous alterations in the abundance of Proteobacteria, Actinomycete, Cyanobacteria, and Stenotrophomonas, Bacteroides, which are associated with intestinal diseases. This evidence concerns the gene MUC2 and intestinal disorder.