GFPT1 and neoplasm: Figure 5F highlights the specific mutated genes within the PI3K pathway. Additionally, when comparing mutation rates between the GFPT1-High BRCA cohort and tumor mutation burdens (TMBs) across various cancer types in the TCGA dataset, BRCA exhibited a median mutation rate, ranking between cholangiocarcinoma and uterine carcinosarcoma (Figure 5G).