STAT3 and neoplasm: Notably, LOC34487-v2 elicited significantly more pronounced inductions in STAT3 phosphorylation than LOC344887-v1 transcript, implicating a potential mechanism through which LOC344887 mediated cellular migration and proliferation as observed in Figure 2B and 2C. To ratify LOC344887-mediated STAT3 phosphorylation in vivo, xenografts from J7 tumor-bearing models were evaluated for their expression of p-STAT3.