In addition, it is reported that cardiomyocyte induced by hypoxia/reoxygenation (H/R) possesses higher expression of cGAS-STING, and either the inhibition of cGAS with RU.521 or suppression of STING with H151 can mitigate the cell apoptosis and cardiac disruption after MI/R, probably via regulation for Bcl‐2/Bax/Caspase‐3 signaling pathways 94. The gene discussed is STING1; the disease is myocardial infarction.