Our previous results confirmed that BRD7 is widely involved in malignant biological processes in NPC, such as cell proliferation, cell cycle progression, apoptosis, invasion and metastasis, by negatively regulating the Ras/MEK/ERK, Rb/E2F, Wnt/β-catenin and PTEN/AKT signaling pathways 8, 9. The gene discussed is BRD7; the disease is nasopharyngeal carcinoma.