Several genes associated with N-linked glycosylation are downregulated in human NASH, indicating a possible perturbation; this observation is supported by an increase in unglycosylated OATP1B1, OATP1B3, OATP2B1, and NTCP in human NASH patients.32 This evidence concerns the gene SLCO1B1 and metabolic dysfunction-associated steatohepatitis.