Slco1a4 mRNA increased to 168% of control (Fig. 4B, upper right panel), to 181% in Mrp2–/–-NASH mice compared to control (Fig. 4B, upper right panel), and was not detected in the Slco1a/1b knockout groups (Fig. 4A, upper right panel). The gene discussed is ABCC2; the disease is metabolic dysfunction-associated steatohepatitis.