KCNN4 and acute respiratory distress syndrome: Petersen G and his colleagues investigated the effect of senicapoc in a porcine two-hit (lung lavage plus injurious MV) model of ARDS, and reported that the blocker of calcium-activated potassium channels (KCa3.1), senicapoc, decreased the number of neutrophils in the alveolar space and lung hemorrhage, although it did not improve oxygenation (93).