The biomarker with the best discrimination capacity for severe COVID-19 was IL6, with an AUROC of 0.79 (95%CI: 0.66 to 0.93), closely followed by IP10 and CRP (AUROCs of 0.78, 95% CI 0.68 to 0.89; and 0.78, 95% CI 0.67 to 0.89). Here, CXCL10 is linked to COVID-19.