Of the 39 biomarkers of interest, 11 biomarkers showed an overall significant difference in median baseline biomarker levels based on hospitalization and COVID-19 severity up to day 28, including CRP, ferritin, IFNα, IL6, IL8, IL1RA, IP10, MCP1, RANTES, suPAR, and lymphocytes (Figure 1). The gene discussed is CRP; the disease is COVID-19.