Furthermore, the application of anti-c-MET-CAR-T cells and CAR-NK cells against gastric cancer cells and glioblastoma has unveiled their potential, exemplified by enhanced IL-2 secretion and cytotoxicity against c-MET+ cancer cells in a xenograft mouse model hosting MKN-45 metastatic gastric cancer cells with c-MET amplification, c-MET-CAR-T cells demonstrated substantial impact (124) (Figure 6B). The gene discussed is MET; the disease is glioblastoma.