Thirteen factors were statistically significant: short disease duration, CRP, Ro-52 positivity, MDA5 antibodies, age, male, lymphocytes, Lactate Dehydrogenase (LDH), Serum Ferritin (SF), Carcinoembryonic Antigen (CEA), fever, arthritis, and muscle weakness; only Aspartate Aminotransferase (AST) and Alanine Aminotransferase (ALT) were not statistically significant. This evidence concerns the gene TRIM21 and arthritic joint disease.