In support of this, the pro-survival BCL2 protein is elevated in CLL [3-5], with the latter often associated with del(13q) [6,7], a chromosomal anomaly that deletes two BCL2 regulatory micro-RNA (miR), miR15a and miR16-1 [6-9]. The gene discussed is BCL2; the disease is B-cell chronic lymphocytic leukemia.