In CRC patients, prognosis of patients with high EGFR or MUC1 expression alone was slightly worse than low expression (Supplementary Figures 3E–H), while the prognosis of patients with high expression of both EGFR and MUC1 was significantly worse than that of patients with low expression levels of both targets (Figures 6C, D, p-value=0.045 for OS, p-value=0.053 for DFI). This evidence concerns the gene EGFR and colorectal carcinoma.