- Targets colonic MUC2 mucin, stimulating over-secretion of goblet cells (Leon-Coria et al., 2018).- Impacts vesicle SNARE VAMP8, crucial for proper mucus secretion (Cornick et al., 2017).- Infection compromises mucosal barrier and triggers increased secretion of pro-inflammatory cytokines (Cornick et al., 2017).- Symptomatic infections associated with gut microbiota dysbiosis (Leon-Coria et al., 2020).- Lactobacillus acidophilus reduces E. histolytica survival by triggering oxidation of crucial amebic enzymes (Sarid et al., 2022). This evidence concerns the gene MUC5AC and infection.