The enrichment of the ‘NF–κ B signalling pathway’, ‘B cell receptor signalling pathway’, and ‘intestinal immune network for IgA production’ suggested that the addition of berberine to the diet may regulate the upregulation or downregulation of key genes in these pathways, thereby balancing the inflammatory and immune responses induced by Salmonella infection. Here, CD79A is linked to Salmonella Infections.