Additionally, combination therapy with the cholesterol‐catalyzed hydrogel plus an anti‐PD‐L1 antibody after iMWA significantly increased the frequency of tumor‐infiltrating CD3+CD8+ cells inside distant tumors (Figure 7F; Figures S10,S12 and S13B, Supporting Information) and reduced the invasion of immunosuppressive T regulatory cells (Tregs) (Figure 7G; Figures S11,S12 and S13C, Supporting Information), significantly increasing the ratio of CD3+CD8+/Tregs in distant tumors (Figure 7H). Here, CD274 is linked to neoplasm.