The IL-8 levels in three CFS were 469.22 ± 6.99 pg/ml, 572.39 ± 20.25 pg/ml, and 480.43 ± 15.09 pg/ml (respectively, CLJ24, JRD1, and JRD6). Here, CXCL8 is linked to myalgic encephalomeyelitis/chronic fatigue syndrome.