The initial full‐length sequencing of common genes implicated in progeroid syndromes, such as LaminA/C, ZMPSTE24, POLD1, and BNF1, revealed homozygous base pair mutations in exon 9 of LaminA/C c.1579C>T (p.R527C) in three patients (here referred to as MAD1, MAD2, MAD3). Here, POLD1 is linked to progeroid syndrome.