EBP and Duchenne muscular dystrophy: To assess the requirement for the binding of Wnt7a with Coatomer for muscle regeneration in vivo, we electroporated the Tibialis Anterior (TA) muscle of male mdx mice, a mouse model of DMD, with vectors expressing either full-length Wnt7a (Wnt7a-FL) and control vector in the contralateral leg or Wnt7a with the EBP replaced with a GSGS linker (Wnt7a_ΔEBP*GSGS) and control vector in the contralateral (Fig. 6D) and analyzed after 21 days.