For the full cohort at 3 years post-SC, we found significant spearman correlations of time between SC and AIDS with 92BR020 gp120-specific Fc features for IgG1, FcγRI, FcγRIIa, FcγRIIIa, FcγRIIb and C1q, with correlation coefficients between 0.18 and 0.28 (Fig 1B). Here, ITIH4 is linked to AIDS.