PTEN and cancer: Impaired autophagic degradation and overexpression of lncRNA ARHGAP5‐AS1 was observed in gastric cancer, which recruits METTL3 for m6A‐mediated stabilization of ARHGAP5 mRNA rendering cancer cells resistant to doxorubicin, cisplatin and 5‐FU.[68] Another lncRNA, LINC00470, recruits METTL3 and increases m6A modification on PTEN mRNA resulting in PTEN degradation in AML.