ALKBH5 and breast carcinoma: ALKBH5 demethylates the 3′‐UTR of the nascent transcripts of the transcription factor FOXM1 protecting it from m6A recognition and degradation by HuR, thus stabilizing and enhancing FOXM1 expression in patient‐derived GSCs.[47] ALKBH5, on the other hand, targets and regulates expression of TACC3 which plays an important role in LSC/LIC self‐renewal.[48] A contrasting effect of ALKBH5 has been observed in breast cancer stem cell (BCSC) enrichment due to the hypoxic stress of breast cancer cells.