H2AX and cancer: The DNA damage repair regulator and checkpoint protein, H2A histone family member X (H2AX), is the target of METTL3 which upon m6A methylation is upregulated; this leads to decreased sensitivity of cancer cells to carbon‐ion radiotherapy.[119] METTL3 upregulation and increased m6A in lncRNA LINC00839 are associated with radiation resistance in GSCs.