Increased m6A in the MRP1 transcript is further recognized by the m6A reader YTHDF1 and eEF‐1 which enhances translation of MRP1 mRNA causing its overexpression in the cancerous cells leading to imatinib resistance due to increased drug efflux.[57] METTL3 is also upregulated in ccRCC where it causes m6A methylation at the 5′‐UTR of the ABC transporter ABCD1 mRNA, enhancing its translation. The gene discussed is METTL3; the disease is nonpapillary renal cell carcinoma.