She also met 5 of the 17 lupus criteria according to the 2012 Systemic Lupus International Collaborating Clinics (SLICC) classification criteria: arthritis, hemolytic anemia, kidney disorder (proteinuria of > 500 mg per 24 h), positive ANA, and low complement (low C3), which includes three clinical and two immunological items. This evidence concerns the gene BTG3 and systemic lupus erythematosus.