Specific transporters such as NHE3, AQP7, and SGLT1, but not cystic fibrosis transmembrane conductance regulator (CFTR), require MYO5B for their correct targeting to the apical brush border [40] and mutations in the MYO5B gene have been linked to the congenital diarrheal disorder MVID caused by the mislocalization of membrane transporters that maintain cell and fluid homeostasis [41]. This evidence concerns the gene MYO5B and microvillus inclusion disease.