A recent study found that Fn induces the secretion of pro-inflammatory cytokines, including CCL2 and CXCL1, through bacterial surface adhesin Fap2 (25), DNA hunger/stationary phase protective proteins (Dps) (56), or CXCL2-mediated crosstalk between tumor cells and macrophages (57). This evidence concerns the gene CCL2 and neoplasm.