Recently, some researchers have found a persistent increasing memory B‐cell subset with lower inhibitory Fc gamma receptor IIB (FcγRIIB) expression in both typical CIDP and CIDP variants patients, which might fail to prevent memory B cells with self‐reactive receptors from entering the germinal center and becoming IgG‐positive plasma cells, thereby causing a chronic overactivity in the B‐cell mediated humoral immunity.31, 32, 33. Here, FCGR2B is linked to chronic inflammatory demyelinating polyradiculoneuropathy.