(99) demonstrated that neutrophils and neutrophil extracellular traps (NETs) play crucial roles in AAN, and proposed that therapeutic targets targeting PSTPIP2/nuclear factor (NF)-κB/IL-19/IL-20Rβ could offer novel strategies for reducing aristolochic acid I-mediated acute kidney injury and apoptosis. Here, PSTPIP2 is linked to acute kidney injury.