In the context of cardiovascular diseases, EMT is a crucial factor in various pathological conditions (32), including atherosclerosis, vascular remodeling, cardiac fibrosis, heart valve diseases, and myocardial infarction, involving different signaling pathways and molecular mechanisms such as TGF-β, Notch signaling, Wnt/β-catenin, and inflammatory cytokines (33–35). This evidence concerns the gene TGFB1 and atherosclerosis.