In this article, we report a case of a boy with BMD who had a de novo c.31 + 6 T > C heterozygous mutation in exon 1 of the DMD gene with co-morbid ADHD, and after treating the child with methylphenidate and rehabilitating him, his attention, motor endurance, and motor balance improved compared with the previous one, and the results of our findings broaden the spectrum of causative mutations of BMD, as well as provide value for future therapeutic options for children with BMD combined with ADHD. This evidence concerns the gene DMD and Becker muscular dystrophy.