During treatment, his anemia worsened, and his anemia-related examination results were as follows: serum ferritin, 328.50 (NR, 11.0–306.8) ng/mL; serum iron, 32.27 (NR, 11–30) μmol/L; total iron-binding capacity, 38.27 (NR, 45–75) μmol/L; transferrin saturation, 84.32%; serum B12, 574.96 (NR, 180–914) pmol/L; serum folate, 18.76 (NR, 11.8–50.0) nmol/L; and reticulocyte percentage, 2.72% (NR, 0.3–3.0%). The gene discussed is TF; the disease is anemia.