PCNA and neoplasm: Based on a meta-analysis of the available data, significant predictors of EUR were identified, including patient-specific factors [such as proliferating cell nuclear antigen Ki-67, preoperative neutrophil-to-lymphocyte ratio (NLR), and preoperative estimated glomerular filtration rate (eGFR)], tumor-specific factors (such as tumor stage, lymphovascular invasion, and lymph node status), and treatment-specific factors (such as positive surgical margins and adjuvant chemotherapeutic regimens).