However, another study found that H19 was highly expressed in melanoma tissues compared to normal paraneoplastic skin tissues, and the level of expression in tissues was significantly higher in patients with metastatic melanoma than in those without distant metastases, suggesting that H19 might regulate the growth, invasion, migration, and epithelial mesenchymal transition (MET) of melanoma cells (42). Here, H19 is linked to metastatic melanoma.