H19 and neoplasm: Apart from this, H19 also functions as ceRNAs to silence target mRNAs by sponging target miRNAs such as inhibiting miR-138 and facilitating EZH2 expression in OSCC8 or by sponging miRNA let-7a, the key regulator of tumor metastasis HMGA2, playing a critical role in the regulation of TSCC migration and invasions (15).