Although this study is not intended to compare the regulation of c-Myc between NSCLC and HGSOC cell lines, we observed that the upregulation of c-Myc in PPP2R2A-deficient cells occurs through an eIF4EBP1-associated translation mechanism in NSCLC 39, whereas in HGSOC, a transcriptional regulatory mechanism is involved (Figure 5). The gene discussed is EIF4EBP1; the disease is non-small cell lung carcinoma.