Our previous study suggests that PP2A B55α regulates c-Myc expression in NSCLC 39 and cMyc activity is required for PPP2R2A deficiency-induced replication initiation/RS and PPP2R2A low expression/deficiency-induced CHK1 inhibitor sensitivity in NSCLC 39. This evidence concerns the gene PPP2R2A and non-small cell lung carcinoma.