At this stage, BCAA-deficient chow did not alter food intake (Figure S3C,D), water intake (Figure S3E,F), fasting blood glucose levels (Figure S3G,H), and insulin resistance, as detected by glucose tolerance tests (Figure S3I,J) and insulin tolerance tests (Figure S3K,L) in both STZ/HFD and db/db mice. Here, INS is linked to Insulin resistance.