SOAT1 and colorectal carcinoma: In CRC, dysregulation of the JAK-STAT pathway has been widely reported, with abnormal signaling profoundly affecting critical biological processes, such as cellular proliferation, survival, migration, invasion, cancer stem cell maintenance, and immune evasion (Liang et al., 2019; Zheng et al., 2022; Ghasemian et al., 2023).