NSD2, also known as Wolf‐Hirschhorn syndrome candidate gene‐1 (WHSC1) or MM overexpresses multiple myeloma SET domain‐containing protein (MMSET), encodes a histone methyltransferase that specifically dimethylates histone H3 at lysine 36 (H3K36me2).11 The gene discussed is NSD2; the disease is Miyoshi myopathy.