T‐cells in the sarcoma microenvironment exhibited elevated levels of cytotoxicity (GZMB, GNLY and KLRD1), exhaustion (HAVCR2, CD38, CD160, CXCL13 and CX3CR1), and inflammation (IL33, PPARG, IL6R and SOCS3), suggesting an activated but exhausted phenotype (Figure 2E). This evidence concerns the gene CD38 and sarcoma.